DDX58 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DDX58 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DDX58 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DDX58 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DDX58
Entrez GeneID
23586GeneBank Accession#
DDX58Gene Name
DDX58
Gene Alias
DKFZp434J1111, DKFZp686N19181, FLJ13599, RIG-I
Gene Description
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Omim ID
609631Gene Ontology
HyperlinkGene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq
Other Designations
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I|OTTHUMP00000021185|OTTHUMP00000045225|RNA helicase RIG-I|retinoic acid-inducible gene I
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Interactome
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Disease
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