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DDX58 rabbit monoclonal antibody

  • Catalog # : H00023586-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DDX58 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DDX58 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DDX58 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • DDX58
  • Gene Name:
  • DDX58
  • Gene Alias:
  • DKFZp434J1111,DKFZp686N19181,FLJ13599,RIG-I
  • Gene Description:
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
  • Gene Summary:
  • DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq
  • Other Designations:
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide,DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I,OTTHUMP00000021185,OTTHUMP00000045225,RNA helicase RIG-I,retinoic acid-inducible gene I
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