CCNDBP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CCNDBP1 partial ORF ( NP_036274.2, 261 a.a. - 360 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LVAENGKKDQVAQMADIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (81); Rat (77)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CCNDBP1
Entrez GeneID
23582GeneBank Accession#
NM_012142Protein Accession#
NP_036274.2Gene Name
CCNDBP1
Gene Alias
DIP1, GCIP
Gene Description
cyclin D-type binding-protein 1
Omim ID
607089Gene Ontology
HyperlinkGene Summary
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq
Other Designations
D-type cyclin-interacting protein 1|HHM Protein|MAID protein|grap2 cyclin interacting protein
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