ZNF346 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ZNF346 full-length ORF ( NP_036411.1, 1 a.a. - 294 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.3
Interspecies Antigen Sequence
Mouse (84); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ZNF346
Entrez GeneID
23567GeneBank Accession#
NM_012279.2Protein Accession#
NP_036411.1Gene Name
ZNF346
Gene Alias
DKFZp547M223, JAZ, Zfp346
Gene Description
zinc finger protein 346
Omim ID
605308Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq
Other Designations
double-stranded RNA-binding zinc finger protein JAZ
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