ZNF346 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ZNF346 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ZNF346 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ZNF346 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ZNF346
Entrez GeneID
23567GeneBank Accession#
ZNF346Gene Name
ZNF346
Gene Alias
DKFZp547M223, JAZ, Zfp346
Gene Description
zinc finger protein 346
Omim ID
605308Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq
Other Designations
double-stranded RNA-binding zinc finger protein JAZ
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Interactome
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