CLDN14 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CLDN14 protein.
Immunogen
CLDN14 (NP_036262.1, 1 a.a. ~ 239 a.a) full-length human protein.
Sequence
MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CLDN14 MaxPab rabbit polyclonal antibody. Western Blot analysis of CLDN14 expression in mouse spleen.Western Blot (Transfected lysate)
Western Blot analysis of CLDN14 expression in transfected 293T cell line (H00023562-T02) by CLDN14 MaxPab polyclonal antibody.
Lane 1: CLDN14 transfected lysate(25.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CLDN14
Entrez GeneID
23562GeneBank Accession#
NM_012130.2Protein Accession#
NP_036262.1Gene Name
CLDN14
Gene Alias
DFNB29
Gene Description
claudin 14
Omim ID
605608Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000109045|OTTHUMP00000109046|OTTHUMP00000109047|OTTHUMP00000109048|OTTHUMP00000109049
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