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Last updated: 2016/10/16
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CLDN14 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00023562-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human CLDN14 protein.
  • Immunogen:
  • CLDN14 (NP_036262.1, 1 a.a. ~ 239 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of CLDN14 expression in transfected 293T cell line (H00023562-T01) by CLDN14 MaxPab polyclonal antibody.

    Lane 1: CLDN14 transfected lysate(26.29 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • CLDN14
  • Gene Alias:
  • DFNB29
  • Gene Description:
  • claudin 14
  • Gene Summary:
  • Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000109045,OTTHUMP00000109046,OTTHUMP00000109047,OTTHUMP00000109048,OTTHUMP00000109049
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