SNAPAP polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (10.67 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SNAPAP.
Immunogen
SNAPAP (NP_036569.1, 41 a.a. ~ 136 a.a) partial recombinant protein with GST tag.
Sequence
DSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDSGIYPPGSPGK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (10.67 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SNAPIN
Entrez GeneID
23557GeneBank Accession#
NM_012437Protein Accession#
NP_036569.1Gene Name
SNAPIN
Gene Alias
SNAPAP
Gene Description
SNAP-associated protein
Omim ID
607007Gene Ontology
HyperlinkGene Summary
SNAPAP is a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion (Ilardi et al., 1999 [PubMed 10195194]). SNAPAP is also a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM
Other Designations
OTTHUMP00000035157|SNAP-25-binding protein|SNARE associated protein snapin
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Interactome
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Publication Reference
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LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
Yun HJ, Park J, Ho DH, Kim H, Kim CH, Oh H, Ga I, Seo H, Chang S, Son I, Seol W.
Experimental & Molecular Medicine 2013 Aug; 45:e36.
Application：WB-Ti, Mouse, Brain.
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LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
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