PIK3R5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PIK3R5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PIK3R5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PIK3R5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PIK3R5
Entrez GeneID
23533GeneBank Accession#
PIK3R5Gene Name
PIK3R5
Gene Alias
F730038I15Rik, FOAP-2, P101-PI3K, p101
Gene Description
phosphoinositide-3-kinase, regulatory subunit 5
Omim ID
611317Gene Ontology
HyperlinkGene Summary
Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM
Other Designations
phosphoinositide-3-kinase, regulatory subunit 5, p101|phosphoinositide-3-kinase, regulatory subunit, polypeptide p101
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