NNT (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NNT full-length ORF ( AAH32370, 1 a.a. - 207 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
48.51
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NNT
Entrez GeneID
23530GeneBank Accession#
BC032370Protein Accession#
AAH32370Gene Name
NNT
Gene Alias
MGC126502, MGC126503
Gene Description
nicotinamide nucleotide transhydrogenase
Omim ID
607878Gene Ontology
HyperlinkGene Summary
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
NAD(P) transhydrogenase|OTTHUMP00000122433|pyridine nucleotide transhydrogenase
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Interactome
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Pathway
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