CABIN1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CABIN1 partial ORF ( NP_036427, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CABIN1
Entrez GeneID
23523GeneBank Accession#
NM_012295Protein Accession#
NP_036427Gene Name
CABIN1
Gene Alias
CAIN, KIAA0330, PPP3IN
Gene Description
calcineurin binding protein 1
Omim ID
604251Gene Ontology
HyperlinkGene Summary
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. At least four alternatively spliced transcripts have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq
Other Designations
calcineurin binding protein cabin 1|calcineurin inhibitor
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Interactome
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Disease
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