HEY2 monoclonal antibody (M02), clone 2B10
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More Files
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Western Blot (Tissue lysate)
HEY2 monoclonal antibody (M02), clone 2B10. Western Blot analysis of HEY2 expression in human pancreas.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HEY2 is 3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HEY2.
Immunogen
HEY2 (NP_036391.1, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HEY2 monoclonal antibody (M02), clone 2B10. Western Blot analysis of HEY2 expression in human pancreas.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HEY2 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — HEY2
Entrez GeneID
23493GeneBank Accession#
NM_012259Protein Accession#
NP_036391.1Gene Name
HEY2
Gene Alias
CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, MGC10720, bHLHb32
Gene Description
hairy/enhancer-of-split related with YRPW motif 2
Omim ID
604674Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq
Other Designations
HES-related repressor protein 1|OTTHUMP00000017138|cardiovascular basic helix-loop-helix factor 1|hairy-related transcription factor 2
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Interactome
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Disease
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