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Last updated: 2016/11/27

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HEY2 rabbit monoclonal antibody

  • Catalog # : H00023493-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human HEY2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human HEY2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human HEY2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • HEY2
  • Gene Name:
  • HEY2
  • Gene Alias:
  • CHF1,GRIDLOCK,GRL,HERP1,HESR2,HRT2,MGC10720,bHLHb32
  • Gene Description:
  • hairy/enhancer-of-split related with YRPW motif 2
  • Gene Summary:
  • This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • HES-related repressor protein 1,OTTHUMP00000017138,cardiovascular basic helix-loop-helix factor 1,hairy-related transcription factor 2
  • Related Disease
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