PES1 MaxPab mouse polyclonal antibody (B02)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PES1 protein.
Immunogen
PES1 (NP_055118, 1 a.a. ~ 588 a.a) full-length human protein.
Sequence
MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEFPTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (90)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
PES1 MaxPab polyclonal antibody. Western Blot analysis of PES1 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of PES1 expression in transfected 293T cell line (H00023481-T02) by PES1 MaxPab polyclonal antibody.
Lane 1: PES1 transfected lysate(64.68 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PES1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PES1
Entrez GeneID
23481GeneBank Accession#
NM_014303Protein Accession#
NP_055118Gene Name
PES1
Gene Alias
PES
Gene Description
pescadillo homolog 1, containing BRCT domain (zebrafish)
Omim ID
605819Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression. [provided by RefSeq
Other Designations
pescadillo homolog 1, containing BRCT domain
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Interactome
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Publication Reference
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mTOR signaling regulates the processing of pre-rRNA in human cells.
Iadevaia V, Zhang Z, Jan E, Proud CG.
Nucleic Acids Research 2012 Mar; 40(6):2527.
Application:WB-Ce, Human, HeLa cells.
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mTOR signaling regulates the processing of pre-rRNA in human cells.
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