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ISCU rabbit monoclonal antibody

  • Catalog # : H00023479-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ISCU peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ISCU is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ISCU peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • ISCU
  • Gene Name:
  • ISCU
  • Gene Alias:
  • 2310020H20Rik,HML,ISU2,MGC74517,NIFU,NIFUN,hnifU
  • Gene Description:
  • iron-sulfur cluster scaffold homolog (E. coli)
  • Gene Summary:
  • Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq
  • Other Designations:
  • IscU iron-sulfur cluster scaffold homolog,NifU-like N-terminal domain containing,iron-sulfur cluster assembly enzyme,nitrogen fixation cluster-like
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