ICMT (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ICMT partial ORF ( NP_036537, 86 a.a. - 154 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.33
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ICMT
Entrez GeneID
23463GeneBank Accession#
NM_012405Protein Accession#
NP_036537Gene Name
ICMT
Gene Alias
HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Gene Description
isoprenylcysteine carboxyl methyltransferase
Omim ID
605851Gene Ontology
HyperlinkGene Summary
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000001381|prenylated protein carboxyl methyltransferase|prenylcysteine carboxyl methyltransferase|protein-S isoprenylcysteine O-methyltransferase
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Interactome
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Disease
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