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ICMT rabbit monoclonal antibody

  • Catalog # : H00023463-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ICMT peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ICMT is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ICMT peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • ICMT
  • Gene Name:
  • ICMT
  • Gene Alias:
  • HSTE14,MGC39955,MST098,MSTP098,PCCMT,PCMT,PPMT
  • Gene Description:
  • isoprenylcysteine carboxyl methyltransferase
  • Gene Summary:
  • This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000001381,prenylated protein carboxyl methyltransferase,prenylcysteine carboxyl methyltransferase,protein-S isoprenylcysteine O-methyltransferase
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