ANGPTL2 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human ANGPTL2 full-length ORF ( AAH12368.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYAFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEERCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
79.75
Interspecies Antigen Sequence
Mouse (95); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ANGPTL2
Entrez GeneID
23452GeneBank Accession#
BC012368Protein Accession#
AAH12368.1Gene Name
ANGPTL2
Gene Alias
ARP2, HARP, MGC8889
Gene Description
angiopoietin-like 2
Omim ID
605001Gene Ontology
HyperlinkGene Summary
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq
Other Designations
OTTHUMP00000022159|angiopoietin-related protein 2
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Interactome
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Publication Reference
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ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer.
Xiangxiang Liu, Jian Qin, Junjie Nie, Rui Gao, Shangshang Hu, Huiling Sun, Shukui Wang, Yuqin Pan.
Frontiers in Immunology 2023 Aug; 14:1185208.
Application：Transfect, Human, Human cancer-associated fibroblasts.
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ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer.
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