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SF3B3 Pre-design Chimera RNAi

  • Catalog # : H00023450-R01
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  • Specification
  • Product Description:
  • Homo sapiens splicing factor 3b, subunit 3, 130kDa (SF3B3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_012426
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • SF3B3
  • Gene Alias:
  • KIAA0017,RSE1,SAP130,SF3b130,STAF130
  • Gene Description:
  • splicing factor 3b, subunit 3, 130kDa
  • Gene Summary:
  • This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq
  • Other Designations:
  • pre-mRNA splicing factor SF3b, 130 kDa subunit,spliceosome-associated protein 130,splicing factor 3b, subunit 3
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