GPR161 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GPR161 partial ORF ( NP_722561.1, 362 a.a. - 460 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SNRITDLGLSPHLTALMAGGQPLGHSSSTGDTGFSCSQDSGTDMMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GPR161
Entrez GeneID
23432GeneBank Accession#
NM_153832Protein Accession#
NP_722561.1Gene Name
GPR161
Gene Alias
FLJ33952, RE2
Gene Description
G protein-coupled receptor 161
Gene Ontology
HyperlinkGene Summary
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM
Other Designations
G-protein coupled receptor|OTTHUMP00000032585|OTTHUMP00000032586|OTTHUMP00000032587
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Interactome
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Disease
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