GPR161 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GPR161 peptide using ARM Technology.
Immunogen
A synthetic peptide of human GPR161 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GPR161 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GPR161
Entrez GeneID
23432GeneBank Accession#
GPR161Gene Name
GPR161
Gene Alias
FLJ33952, RE2
Gene Description
G protein-coupled receptor 161
Gene Ontology
HyperlinkGene Summary
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM
Other Designations
G-protein coupled receptor|OTTHUMP00000032585|OTTHUMP00000032586|OTTHUMP00000032587
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Interactome
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Disease
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