TPSD1 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human TPSD1 full-length ORF ( NP_036349.1, 1 a.a. - 242 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
53
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TPSD1
Entrez GeneID
23430GeneBank Accession#
NM_012217.2Protein Accession#
NP_036349.1Gene Name
TPSD1
Gene Alias
MCP7-LIKE, MCP7L1, MGC95428, MMCP-7L
Gene Description
tryptase delta 1
Omim ID
609272Gene Ontology
HyperlinkGene Summary
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq
Other Designations
hmMCP-3-like tryptase III|hmMCP-7-like|mMCP-7-like delta II tryptase|mMCP-7-like-1|mMCP-7-like-2|mast cell protease 7-like|mast cell tryptase
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