MLYCD purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MLYCD protein.
Immunogen
MLYCD (NP_036345.2, 1 a.a. ~ 493 a.a) full-length human protein.
Sequence
MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKTPAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAAVLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNGVLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFFSHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQGVELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSECKEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVANFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQVLSLVAQFQKNSKL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MLYCD expression in transfected 293T cell line (H00023417-T01) by MLYCD MaxPab polyclonal antibody.
Lane 1: MLYCD transfected lysate(54.23 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MLYCD
Entrez GeneID
23417GeneBank Accession#
NM_012213.2Protein Accession#
NP_036345.2Gene Name
MLYCD
Gene Alias
MCD, MGC59795
Gene Description
malonyl-CoA decarboxylase
Gene Ontology
HyperlinkGene Summary
The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq
Other Designations
malonyl coenzyme A decarboxylase
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Interactome
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Pathway
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Disease
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Publication Reference
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Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus.
Kulkarni SS, Salehzadeh F, Fritz T, Zierath JR, Krook A, Osler ME.
Metabolism: Clinical and Experimental 2012 Feb; 61(2):175.
Application:WB-Ti, Human, Human skeletal muscle lysates.
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Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus.
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