FREQ monoclonal antibody (M02), clone 3E7
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant FREQ.
Immunogen
FREQ (AAH04856, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (46.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FREQ is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — FREQ
Entrez GeneID
23413GeneBank Accession#
BC004856Protein Accession#
AAH04856Gene Name
FREQ
Gene Alias
DKFZp761L1223, FLUP, NCS-1, NCS1
Gene Description
frequenin homolog (Drosophila)
Omim ID
603315Gene Ontology
HyperlinkGene Summary
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022356|frequenin homolog|frequenin-like ubiquitous protein|neuronal calcium sensor 1
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Interactome
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Disease
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