FREQ rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human FREQ peptide using ARM Technology.
Immunogen
A synthetic peptide of human FREQ is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human FREQ peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — FREQ
Entrez GeneID
23413GeneBank Accession#
FREQGene Name
FREQ
Gene Alias
DKFZp761L1223, FLUP, NCS-1, NCS1
Gene Description
frequenin homolog (Drosophila)
Omim ID
603315Gene Ontology
HyperlinkGene Summary
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022356|frequenin homolog|frequenin-like ubiquitous protein|neuronal calcium sensor 1
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Interactome
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Disease
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