COTL1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human COTL1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKSELKKAGGANYDAQTE
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — COTL1
Entrez GeneID
23406GeneBank Accession#
NM_021149.2Protein Accession#
NP_066972.1Gene Name
COTL1
Gene Alias
CLP, FLJ43657, MGC19733
Gene Description
coactosin-like 1 (Dictyostelium)
Omim ID
606748Gene Ontology
HyperlinkGene Summary
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq
Other Designations
coactosin-like 1
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Interactome
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Disease
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