COTL1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human COTL1 full-length ORF ( AAH10884, 1 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKSELKKAGGANYDAQTE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.36
Interspecies Antigen Sequence
Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COTL1
Entrez GeneID
23406GeneBank Accession#
BC010884Protein Accession#
AAH10884Gene Name
COTL1
Gene Alias
CLP, FLJ43657, MGC19733
Gene Description
coactosin-like 1 (Dictyostelium)
Omim ID
606748Gene Ontology
HyperlinkGene Summary
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq
Other Designations
coactosin-like 1
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Interactome
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Disease
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