DICER1 monoclonal antibody (M01A), clone 2F12
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More Files
- More Functions
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DICER1.
Immunogen
DICER1 (NP_803187, 1813 a.a. ~ 1912 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DICER1
Entrez GeneID
23405GeneBank Accession#
NM_177438Protein Accession#
NP_803187Gene Name
DICER1
Gene Alias
DCR1, Dicer, HERNA, KIAA0928
Gene Description
dicer 1, ribonuclease type III
Omim ID
606241Gene Ontology
HyperlinkGene Summary
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
Dicer1, Dcr-1 homolog|K12H4.8-LIKE|dicer 1, double-stranded RNA-specific endoribonuclease|dicer1|helicase with RNAse motif|helicase-moi
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Interactome
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Disease
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Publication Reference
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Cleavage of Dicer Protein by I7 Protease during Vaccinia Virus Infection.
Chen JS, Li HC, Lin SI, Yang CH, Chien WY, Syu CL, Lo SY.
PLoS One 2015 Mar; 10(3):e0120390.
Application：WB-Tr, Human, HeLa, HeLa-mock, HeLa-T7-Dicer cells.
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Cleavage of Dicer Protein by I7 Protease during Vaccinia Virus Infection.
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