NUDCD3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NUDCD3 full-length ORF ( AAH03691.1, 1 a.a. - 220 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKCVLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.1
Interspecies Antigen Sequence
Mouse (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NUDCD3
Entrez GeneID
23386GeneBank Accession#
BC003691.2Protein Accession#
AAH03691.1Gene Name
NUDCD3
Gene Alias
KIAA1068, NudCL
Gene Description
NudC domain containing 3
Omim ID
610296Gene Ontology
HyperlinkGene Summary
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq
Other Designations
NudC-like protein|OTTHUMP00000159457
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Interactome
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Disease
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