PPP1R13B monoclonal antibody (M04), clone 6H1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PPP1R13B.
Immunogen
PPP1R13B (NP_056131.2, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDHMMYEHLQKWGPRREEVKFFLRHEDSPTENS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PPP1R13B is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — PPP1R13B
Entrez GeneID
23368GeneBank Accession#
NM_015316.2Protein Accession#
NP_056131.2Gene Name
PPP1R13B
Gene Alias
ASPP1, KIAA0771, p53BP2-like, p85
Gene Description
protein phosphatase 1, regulatory (inhibitor) subunit 13B
Omim ID
606455Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq
Other Designations
apoptosis-stimulating protein of p53, 1
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Interactome
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Disease
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