UBR2 polyclonal antibody (A01)

Catalog # H00023304-A01

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Size:50 uL
Price: USD $ 243.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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Western Blot detection against Immunogen (37.11 KDa) .

  • Specification

    Product Description

    Mouse polyclonal antibody raised against a partial recombinant UBR2.

    Immunogen

    UBR2 (NP_056070, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.

    Sequence

    MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCG

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (93); Rat (93)

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (37.11 KDa) .

    Storage Buffer

    50 % glycerol

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — UBR2

    Entrez GeneID

    23304

    GeneBank Accession#

    NM_015255

    Protein Accession#

    NP_056070

    Gene Name

    UBR2

    Gene Alias

    C6orf133, DKFZp686C08114, KIAA0349, MGC71112, RP3-392M17.3, bA49A4.1, dJ242G1.1, dJ392M17.3

    Gene Description

    ubiquitin protein ligase E3 component n-recognin 2

    Omim ID

    609134

    Gene Ontology

    Hyperlink

    Gene Summary

    Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM

    Other Designations

    OTTHUMP00000016403|OTTHUMP00000016405|OTTHUMP00000039767|OTTHUMP00000039768|ubiquitin ligase E3 alpha-II

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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