SYNE2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (36.89 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SYNE2.
Immunogen
SYNE2 (NP_055995, 6702 a.a. ~ 6799 a.a) partial recombinant protein with GST tag.
Sequence
CRRELMQLEKELVERQPQVDMLQEISNSLLIKGHGEDCIEAEEKVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.89 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SYNE2
Entrez GeneID
23224GeneBank Accession#
NM_015180Protein Accession#
NP_055995Gene Name
SYNE2
Gene Alias
DKFZp434H2235, DKFZp686E01115, DKFZp686H1931, FLJ11014, FLJ43727, FLJ45710, FLJ46790, KIAA1011, NUA, NUANCE, Nesprin-2, SYNE-2
Gene Description
spectrin repeat containing, nuclear envelope 2
Omim ID
608442Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
nesprin 2|nucleus and actin connecting element|synaptic nuclei expressed gene 2
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Interactome
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Disease
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Publication Reference
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A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Muller Glia.
Maddox DM, Collin GB, Ikeda A, Pratt CH, Ikeda S, Johnson BA, Hurd RE, Shopland LS, Naggert JK, Chang B, Krebs MP, Nishina PM.
Investigative Ophthalmology & Visual Science 2015 Jun; 56(6):3776.
Application：WB-Ti, Mouse, Eyes.
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A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Muller Glia.
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