SULF1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SULF1 full-length
Host
Human
Theoretical MW (kDa)
101
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SULF1 antibody (H00023213-B01) by Western Blots.
SDS-PAGE Gel
SULF1 transfected lysate.
Western Blot
Lane 1: SULF1 transfected lysate ( 101 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SULF1
Entrez GeneID
23213GeneBank Accession#
NM_015170Protein Accession#
NP_055985Gene Name
SULF1
Gene Alias
FLJ30905, FLJ38022, FLJ41750, HSULF-1, KIAA1077, SULF-1
Gene Description
sulfatase 1
Omim ID
610012Gene Ontology
HyperlinkGene Summary
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM
Other Designations
sulfatase FP
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Interactome
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Disease
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