SULF1 monoclonal antibody (M01A), clone 1A4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SULF1.
Immunogen
SULF1 (NP_055985.1, 780 a.a. ~ 871 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.86 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SULF1
Entrez GeneID
23213GeneBank Accession#
NM_015170Protein Accession#
NP_055985.1Gene Name
SULF1
Gene Alias
FLJ30905, FLJ38022, FLJ41750, HSULF-1, KIAA1077, SULF-1
Gene Description
sulfatase 1
Omim ID
610012Gene Ontology
HyperlinkGene Summary
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM
Other Designations
sulfatase FP
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Interactome
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Disease
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