UBXD8 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human UBXD8 full-length ORF ( NP_055428.1, 1 a.a. - 445 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSVFNPPPSRPLQVNTADHRIYSYVVSRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRFIRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGDDHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKDRRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNPPTLQEAGLSHTEVLFVQDLTDE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
79
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FAF2
Entrez GeneID
23197GeneBank Accession#
NM_014613.1Protein Accession#
NP_055428.1Gene Name
FAF2
Gene Alias
ETEA, KIAA0887, UBXD8, UBXN3B
Gene Description
Fas associated factor family member 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq
Other Designations
UBX domain containing 8|UBX domain protein 3B|expressed in T-cells and eosinophils in atopic dermatitis
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Interactome
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Publication Reference
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Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C.
Journal of Neurochemistry 2014 Apr; 129(1):99.
Application：Func, Recombinant protein.
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Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
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