FBXL7 monoclonal antibody (M01), clone 2G10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FBXL7.
Immunogen
FBXL7 (NP_036436, 392 a.a. ~ 489 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
FBXL7 monoclonal antibody (M01), clone 2G10. Western Blot analysis of FBXL7 expression in MCF-7.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FBXL7 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — FBXL7
Entrez GeneID
23194GeneBank Accession#
NM_012304Protein Accession#
NP_036436Gene Name
FBXL7
Gene Alias
FBL6, FBL7
Gene Description
F-box and leucine-rich repeat protein 7
Omim ID
605656Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. [provided by RefSeq
Other Designations
F-box protein Fbl7
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Interactome
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Disease
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