STAB1 monoclonal antibody (M05), clone 4G9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant STAB1.
Immunogen
STAB1 (NP_055951, 1804 a.a. ~ 1902 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged STAB1 is 0.03 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to STAB1 on HUVEC cell . [antibody concentration 10 ug/ml]Immunofluorescence
Immunofluorescence of monoclonal antibody to STAB1 on HeLa cell . [antibody concentration 10 ug/ml]Immunofluorescence
Immunofluorescence of monoclonal antibody to STAB1 on THP-1 cell . [antibody concentration 10 ug/ml]Immunofluorescence
Immunofluorescence of monoclonal antibody to STAB1 on Jurkat cell . [antibody concentration 10 ug/ml] -
Gene Info — STAB1
Entrez GeneID
23166GeneBank Accession#
NM_015136Protein Accession#
NP_055951Gene Name
STAB1
Gene Alias
CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, STAB-1
Gene Description
stabilin 1
Omim ID
608560Gene Ontology
HyperlinkGene Summary
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq
Other Designations
MS-1 antigen|common lymphatic endothelial and vascular endothelial receptor-1|fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1
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Interactome
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Disease
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Publication Reference
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Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model.
Danoy M, Shinohara M, Rizki-Safitri A, Collard D, Senez V, Sakai Y.
Integrative Biology : Quantitative Biosciences from Nano to Macro 2017 Apr; 9(4):350.
Application:IF, Human, Rat, HUVEC, LX-2 cells, Rat hepatocytes.
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Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model.
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