SNX13 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SNX13 transfected lysate.
Western Blot
Lane 1: SNX13 transfected lysate ( 111 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SNX13 full-length
Host
Human
Theoretical MW (kDa)
111
Interspecies Antigen Sequence
Mouse (97); Rat (77)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SNX13 antibody (H00023161-B01) by Western Blots.
SDS-PAGE Gel
SNX13 transfected lysate.
Western Blot
Lane 1: SNX13 transfected lysate ( 111 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SNX13
Entrez GeneID
23161GeneBank Accession#
BC045667.1Protein Accession#
-Gene Name
SNX13
Gene Alias
KIAA0713, RGS-PX1
Gene Description
sorting nexin 13
Omim ID
606589Gene Ontology
HyperlinkGene Summary
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq
Other Designations
rgs domain- and phox domain-containing protein
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Interactome
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Disease
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