NFASC polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
NFASC polyclonal antibody (A01), Lot # 060614JCS1 Western Blot analysis of NFASC expression in HepG2 ( Cat # L019V1 ).
Western Blot detection against Immunogen (36.89 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant NFASC.
Immunogen
NFASC (NP_001005388, 661 a.a. ~ 758 a.a) partial recombinant protein with GST tag.
Sequence
KDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.89 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NFASC polyclonal antibody (A01), Lot # 060614JCS1 Western Blot analysis of NFASC expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — NFASC
Entrez GeneID
23114GeneBank Accession#
NM_001005388Protein Accession#
NP_001005388Gene Name
NFASC
Gene Alias
DKFZp686P2250, FLJ46866, KIAA0756, NF, NRCAML
Gene Description
neurofascin homolog (chicken)
Omim ID
609145Gene Ontology
HyperlinkGene Summary
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined
Other Designations
OTTHUMP00000065305|OTTHUMP00000065306|OTTHUMP00000065307|OTTHUMP00000065308|OTTHUMP00000065313|OTTHUMP00000065315|OTTHUMP00000065321|OTTHUMP00000065322|OTTHUMP00000065324|neurofascin
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Interactome
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Pathway
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Disease
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