CDC2L6 monoclonal antibody (M06), clone 8B6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDC2L6.
Immunogen
CDC2L6 (AAH37289, 367 a.a. ~ 467 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNY
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CDC2L6 expression in transfected 293T cell line by CDC2L6 monoclonal antibody (M06), clone 8B6.
Lane 1: CDC2L6 transfected lysate (Predicted MW: 56.8 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CDC2L6 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — CDC2L6
Entrez GeneID
23097GeneBank Accession#
BC037289Protein Accession#
AAH37289Gene Name
CDC2L6
Gene Alias
CDK11, KIAA1028, bA346C16.3
Gene Description
cell division cycle 2-like 6 (CDK8-like)
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq
Other Designations
CDK8-like cyclin-dependent kinase|OTTHUMP00000017005|OTTHUMP00000040460|cyclin-dependent kinase (CDC2-like) 11|death-preventing kinase
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Interactome
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Disease
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