CDC2L6 monoclonal antibody (M01), clone 3D7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDC2L6.
Immunogen
CDC2L6 (NP_055891.1, 1 a.a. ~ 114 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRAS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CDC2L6 on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CDC2L6 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CDC2L6
Entrez GeneID
23097GeneBank Accession#
NM_015076Protein Accession#
NP_055891.1Gene Name
CDC2L6
Gene Alias
CDK11, KIAA1028, bA346C16.3
Gene Description
cell division cycle 2-like 6 (CDK8-like)
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq
Other Designations
CDK8-like cyclin-dependent kinase|OTTHUMP00000017005|OTTHUMP00000040460|cyclin-dependent kinase (CDC2-like) 11|death-preventing kinase
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Interactome
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Disease
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