PEG10 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PEG10 protein.
Immunogen
PEG10 (NP_001035242.1, 1 a.a. ~ 325 a.a) full-length human protein.
Sequence
MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGNSPAPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (65)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PEG10 MaxPab polyclonal antibody. Western Blot analysis of PEG10 expression in human stomach.Western Blot (Transfected lysate)
Western Blot analysis of PEG10 expression in transfected 293T cell line (H00023089-T01) by PEG10 MaxPab polyclonal antibody.
Lane 1: PEG10 transfected lysate(35.75 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PEG10 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PEG10
Entrez GeneID
23089GeneBank Accession#
NM_001040152Protein Accession#
NP_001035242.1Gene Name
PEG10
Gene Alias
Edr, HB-1, KIAA1051, MEF3L, Mar2, Mart2, RGAG3
Gene Description
paternally expressed 10
Omim ID
609810Gene Ontology
HyperlinkGene Summary
This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas. [provided by RefSeq
Other Designations
MEF3 like 1|embryonal carcinoma differentiation regulated|retrotransposon gag domain containing 3
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