SETX (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SETX partial ORF ( NP_055861.2, 2579 a.a. - 2676 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
VVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (50); Rat (47)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SETX
Entrez GeneID
23064GeneBank Accession#
NM_015046Protein Accession#
NP_055861.2Gene Name
SETX
Gene Alias
ALS4, AOA2, DKFZp781B151, FLJ12840, FLJ43459, KIAA0625, SCAR1, bA479K20.2
Gene Description
senataxin
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq
Other Designations
OTTHUMP00000064564
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Interactome
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Disease
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