SETX monoclonal antibody (M05), clone 2A9
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More Files
- More Functions
Western Blot (Cell lysate)
SETX monoclonal antibody (M05), clone 2A9. Western Blot analysis of SETX expression in NIH/3T3(Cat # L018V1 ).
Western Blot (Cell lysate)
SETX monoclonal antibody (M05), clone 2A9. Western Blot analysis of SETX expression in PC-12(Cat # L012V1 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SETX is 0.3 ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to SETX on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (36.52 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SETX.
Immunogen
SETX (NP_055861.2, 2579 a.a. ~ 2676 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKL
Host
Mouse
Reactivity
Human, Mouse, Rat
Interspecies Antigen Sequence
Mouse (50); Rat (47)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SETX monoclonal antibody (M05), clone 2A9. Western Blot analysis of SETX expression in NIH/3T3(Cat # L018V1 ).Western Blot (Cell lysate)
SETX monoclonal antibody (M05), clone 2A9. Western Blot analysis of SETX expression in PC-12(Cat # L012V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SETX is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SETX on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SETX
Entrez GeneID
23064GeneBank Accession#
NM_015046Protein Accession#
NP_055861.2Gene Name
SETX
Gene Alias
ALS4, AOA2, DKFZp781B151, FLJ12840, FLJ43459, KIAA0625, SCAR1, bA479K20.2
Gene Description
senataxin
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq
Other Designations
OTTHUMP00000064564
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Interactome
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Disease
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