NMNAT2 monoclonal antibody (M02), clone 4E6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NMNAT2.
Immunogen
NMNAT2 (NP_055854, 208 a.a. ~ 307 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
CIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NMNAT2 monoclonal antibody (M02), clone 4E6. Western Blot analysis of NMNAT2 expression in MCF-7.Western Blot (Recombinant protein)
ELISA
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Gene Info — NMNAT2
Entrez GeneID
23057GeneBank Accession#
NM_015039Protein Accession#
NP_055854Gene Name
NMNAT2
Gene Alias
C1orf15, KIAA0479, MGC2756, PNAT-2, PNAT2
Gene Description
nicotinamide nucleotide adenylyltransferase 2
Omim ID
608701Gene Ontology
HyperlinkGene Summary
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000033548|OTTHUMP00000033549|nicotinamide mononucleotide adenylyltransferase 2|pyridine nucleotide adenylyltransferase 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.
Yan T, Feng Y, Zheng J, Ge X, Zhang Y, Wu D, Zhao J, Zhai Q.
Neurochemistry International 2010 Jan; 56(1):101.
Application:WB-Ti, Mouse, Mouse brains.
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Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.
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