NCOA6 (Human) Recombinant Protein (Q01)
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More Files
- More Functions
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Specification
Product Description
Human NCOA6 partial ORF ( NP_054790, 1954 a.a. - 2063 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
VGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NCOA6
Entrez GeneID
23054GeneBank Accession#
NM_014071Protein Accession#
NP_054790Gene Name
NCOA6
Gene Alias
AIB3, ANTP, ASC2, HOX1.1, HOXA7, KIAA0181, NRC, PRIP, RAP250, TRBP
Gene Description
nuclear receptor coactivator 6
Omim ID
605299Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases. [provided by RefSeq
Other Designations
OTTHUMP00000030705|activating signal cointegrator-2|amplified in breast cancer-3 protein|nuclear receptor coactivator RAP250|peroxisome proliferator-activated receptor interacting protein|thyroid hormone receptor binding protein
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Interactome
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Disease
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