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Last updated: 2017/12/10

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SPEN Pre-design Chimera RNAi

  • Catalog # : H00023013-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens spen homolog, transcriptional regulator (Drosophila) (SPEN), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_015001
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • SPEN
  • Gene Alias:
  • KIAA0929,MINT,RP1-134O19.1,SHARP
  • Gene Description:
  • spen homolog, transcriptional regulator (Drosophila)
  • Gene Summary:
  • This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq
  • Other Designations:
  • Msx2 interacting nuclear target (MINT) homolog,OTTHUMP00000010982,OTTHUMP00000044600,SMART/HDAC1 associated repressor protein,nuclear receptor transcription cofactor,spen homolog, transcriptional regulator
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