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Last updated: 2016/12/4

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DAAM1 Pre-design Chimera RNAi

  • Catalog # : H00023002-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens dishevelled associated activator of morphogenesis 1 (DAAM1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014992
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • DAAM1
  • Gene Alias:
  • FLJ41657,KIAA0666
  • Gene Description:
  • dishevelled associated activator of morphogenesis 1
  • Gene Summary:
  • Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000179033,dishevelled-associated activator of morphogenesis 1
  • Gene Pathway
  • Related Disease
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