LTB4DH polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
LTB4DH polyclonal antibody (A01), Lot # 051212JC01 Western Blot analysis of LTB4DH expression in 293 ( Cat # L026V1 ).
Western Blot detection against Immunogen (37 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant LTB4DH.
Immunogen
LTB4DH (NP_036344, 230 a.a. ~ 328 a.a) partial recombinant protein with GST tag.
Sequence
MKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (79)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
LTB4DH polyclonal antibody (A01), Lot # 051212JC01 Western Blot analysis of LTB4DH expression in 293 ( Cat # L026V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PTGR1
Entrez GeneID
22949GeneBank Accession#
NM_012212Protein Accession#
NP_036344Gene Name
PTGR1
Gene Alias
LTB4DH, MGC34943, ZADH3
Gene Description
prostaglandin reductase 1
Omim ID
601274Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
NADP-dependent leukotriene B4 12-hydroxydehydrogenase|OTTHUMP00000021915|leukotriene B4 12-hydroxydehydrogenase|zinc binding alcohol dehydrogenase domain containing 3
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Interactome
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Disease
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Publication Reference
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Up-regulation of human prostaglandin reductase 1 improves the efficacy of hydroxymethylacylfulvene, an antitumor chemotherapeutic agent.
Yu X, Erzinger MM, Pietsch KE, Cervoni-Curet FN, Whang J, Niederhuber J, Sturla SJ.
The Journal of Pharmacology and Experimental Therapeutics 2012 Nov; 343(2):426.
Application：WB, Human, HCT-15, HepG2, SW620 cells.
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Up-regulation of human prostaglandin reductase 1 improves the efficacy of hydroxymethylacylfulvene, an antitumor chemotherapeutic agent.
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