NCBP2 monoclonal antibody (M02), clone 3A12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NCBP2.
Immunogen
NCBP2 (NP_031388, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NCBP2 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — NCBP2
Entrez GeneID
22916GeneBank Accession#
NM_007362Protein Accession#
NP_031388Gene Name
NCBP2
Gene Alias
CBC2, CBP20, NIP1, PIG55
Gene Description
nuclear cap binding protein subunit 2, 20kDa
Omim ID
605133Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
NCBP interacting protein 1|cell proliferation-inducing gene 55
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