MMRN1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MMRN1 partial ORF ( NP_031377, 291 a.a. - 390 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (65); Rat (65)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MMRN1
Entrez GeneID
22915GeneBank Accession#
NM_007351Protein Accession#
NP_031377Gene Name
MMRN1
Gene Alias
ECM, EMILIN4, GPIa*, MMRN
Gene Description
multimerin 1
Omim ID
601456Gene Ontology
HyperlinkGene Summary
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq
Other Designations
OTTHUMP00000161558|glycoprotein Ia*
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Interactome
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Disease
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Publication Reference
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VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets.
Satoh K, Hirayama T, Takano K, Suzuki-Inoue K, Sato T, Ohta M, Nakagomi J, Ozaki Y.
Thrombosis Journal 2013 Nov; 11(1):23.
Application：PI, Recombinant protein.
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VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets.
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